Formation and stabilization of G-quadruplex in nanosized water pools.
نویسندگان
چکیده
We demonstrate here that G-quadruplex structure can form and exhibits strong stability in nanosized water pools, providing new insight into investigating G-quadruplexes in the cellular environment.
منابع مشابه
Formation and stabilization of G-quadruplex in nanosized water poolsw
Guanine-rich oligonucleotides are able to form four-stranded G-quadruplex structures by associating stacks of G-quartets which are stabilized by Hoogsteen hydrogen bonding. Recently, G-quadruplex structures have drawn lots of attention in areas such as biology, medicinal chemistry, supramolecular chemistry and nanotechnology. G-quadruplex structures display great conformational diversity due to...
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ورودعنوان ژورنال:
- Chemical communications
دوره 46 10 شماره
صفحات -
تاریخ انتشار 2010